DEPRESSION OF SERUM ALKALINE PHOSPHATASE ACTIVITY BY HUMAN SERUM ALBUMIN

Depression of serum alkaline phosphatase activity by human serum albumin.

The daily intravenous administration of 50 gm. of concentrated saltpoor human serum albumin’ produces a rise in serum albumin level and a decline in urinary calcium and phosphorus excretion (1). These latter changes have been interpreted as evidence for an albumin-induced stimulation of osteogenesis (2). The consistent finding of a concomitant depression of serum alkaline phosphatase activity w...

Alkaline Phosphatase in Serum is a Marker of Human Toxocariasis

Background: The present study was carried out on the human population of Kashmir valley to evaluate the status of the biochemical parameters of infected population. Materials and Methods: Blood samples were collected from 514 individuals, 298 (57.97%) males and 216 (42.02%) females, 187 (36.38%) were found sero-positive for human toxocariasis. Results: Alkaline phosphatase level was found highe...

Measurement of total alkaline phosphatase activity in human serum.

Evaluators: Bernard E. Statland, Department of Laboratory Medicine and Pathology, Box 198, Mayo Memorial Building, University of Minnesota, Minneapolis, Minn. 55455 Donald S. Young and Maurice Green, Clinical Chemistry Department, National Institutes of Health, Bethesda, Md. 20014 Victor G. Bethune, Jerome S. Nisselbaum, and Morton Schwartz, Department of Biochemistry, Memorial Sloan-Kettering ...

Skeletal alkaline phosphatase activity in serum.

Serum Alkaline Phosphatase

phatase may reflect enzyme contributions from bone, liver, and intestine. We have investigated serum alkaline phosphatases in two siblings with hypophosphatasia. After administration of long-chain triglycerides, the major alkaline phosphatase component of their sera was shown to be of intestinal origin on the basis of inhibition by l-phenylalanine. Starch block electrophoresis suggested that th...